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Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol

Received: 23 December 2014     Accepted: 10 January 2015     Published: 23 January 2015
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Abstract

The influence of the natural complex of low molecular weight compounds (fungidol) on antitoxic and antioxidant systems in animals was investigated. It was demonstrated that the introduction to the experimental animals of fungidol in doses a 0.05 ml per 100 g of body weight increases antioxidant enzymes activity in serum and liver, decreases the content of lipids hydroperoxides and other products of free radical reactions. The components of fungidol antioxidant activity correlated with the stability of membranes of erythrocytes in these animals. In the experimental model the toxic effect of copper sulfate was investigated. The increase in the activity of prooxidant system induced by fungidol correlated with its antitoxic effect.

Published in American Journal of Biomedical and Life Sciences (Volume 2, Issue 6-1)

This article belongs to the Special Issue Mechanisms of Protection Against Oxidative Stress

DOI 10.11648/j.ajbls.s.2014020601.15
Page(s) 25-32
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Antioxidant System, Antitoxic Activity, Prooxidant Activity, Fungidol

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    Natalia Igorevna Kurguzova, Anatoliy Ivanovich Bozhkov, Yuriy Viktorovich Nikitchenko, Mohammad Ali Yousef Al Begai, Anatoliy Vladimirovich Goltvyansky, et al. (2015). Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol. American Journal of Biomedical and Life Sciences, 2(6-1), 25-32. https://doi.org/10.11648/j.ajbls.s.2014020601.15

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    ACS Style

    Natalia Igorevna Kurguzova; Anatoliy Ivanovich Bozhkov; Yuriy Viktorovich Nikitchenko; Mohammad Ali Yousef Al Begai; Anatoliy Vladimirovich Goltvyansky, et al. Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol. Am. J. Biomed. Life Sci. 2015, 2(6-1), 25-32. doi: 10.11648/j.ajbls.s.2014020601.15

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    AMA Style

    Natalia Igorevna Kurguzova, Anatoliy Ivanovich Bozhkov, Yuriy Viktorovich Nikitchenko, Mohammad Ali Yousef Al Begai, Anatoliy Vladimirovich Goltvyansky, et al. Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol. Am J Biomed Life Sci. 2015;2(6-1):25-32. doi: 10.11648/j.ajbls.s.2014020601.15

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  • @article{10.11648/j.ajbls.s.2014020601.15,
      author = {Natalia Igorevna Kurguzova and Anatoliy Ivanovich Bozhkov and Yuriy Viktorovich Nikitchenko and Mohammad Ali Yousef Al Begai and Anatoliy Vladimirovich Goltvyansky and Mohammad Morshed Ayed Alsardia and Andrew Anatolievich Bozhkov},
      title = {Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {2},
      number = {6-1},
      pages = {25-32},
      doi = {10.11648/j.ajbls.s.2014020601.15},
      url = {https://doi.org/10.11648/j.ajbls.s.2014020601.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.s.2014020601.15},
      abstract = {The influence of the natural complex of low molecular weight compounds (fungidol) on antitoxic and antioxidant systems in animals was investigated. It was demonstrated that the introduction to the experimental animals of fungidol in doses a 0.05 ml per 100 g of body weight increases antioxidant enzymes activity in serum and liver, decreases the content of lipids hydroperoxides and other products of free radical reactions. The components of fungidol antioxidant activity correlated with the stability of membranes of erythrocytes in these animals. In the experimental model the toxic effect of copper sulfate was investigated. The increase in the activity of prooxidant system induced by fungidol correlated with its antitoxic effect.},
     year = {2015}
    }
    

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  • TY  - JOUR
    T1  - Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol
    AU  - Natalia Igorevna Kurguzova
    AU  - Anatoliy Ivanovich Bozhkov
    AU  - Yuriy Viktorovich Nikitchenko
    AU  - Mohammad Ali Yousef Al Begai
    AU  - Anatoliy Vladimirovich Goltvyansky
    AU  - Mohammad Morshed Ayed Alsardia
    AU  - Andrew Anatolievich Bozhkov
    Y1  - 2015/01/23
    PY  - 2015
    N1  - https://doi.org/10.11648/j.ajbls.s.2014020601.15
    DO  - 10.11648/j.ajbls.s.2014020601.15
    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
    SP  - 25
    EP  - 32
    PB  - Science Publishing Group
    SN  - 2330-880X
    UR  - https://doi.org/10.11648/j.ajbls.s.2014020601.15
    AB  - The influence of the natural complex of low molecular weight compounds (fungidol) on antitoxic and antioxidant systems in animals was investigated. It was demonstrated that the introduction to the experimental animals of fungidol in doses a 0.05 ml per 100 g of body weight increases antioxidant enzymes activity in serum and liver, decreases the content of lipids hydroperoxides and other products of free radical reactions. The components of fungidol antioxidant activity correlated with the stability of membranes of erythrocytes in these animals. In the experimental model the toxic effect of copper sulfate was investigated. The increase in the activity of prooxidant system induced by fungidol correlated with its antitoxic effect.
    VL  - 2
    IS  - 6-1
    ER  - 

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Author Information
  • Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine

  • Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine

  • Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine

  • Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine

  • Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine

  • Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine

  • Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine

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